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PepRank

CJC-1295 user reports (30)

Glowing 3Positive 7Mixed 4Nothing 4Negative 6Bad reaction 5

30 reports

  • r/BodyHackGuideon Reddit

    Yes yes and yes! Recovery time!!! I dont even get tired after my workouts plus I dont get sore anymore. When I took a break I died.. Im back on it!

    • 15 points
    GlowingRecovery & healing

    CJC/ipa combo

  • r/BodyHackGuideon Reddit

    You will feel like shit for around 2-4 weeks. I started this stack and it took me 4 weeks to get through the loading phase. Felt sluggish and hardly any energy in my cardio runs or out of breath on my ski/row. After I started week 5 it was a drastic change.

    • 10 points
    GlowingRecovery & healing7 weeks

    CJC no-DAC + ipamorelin, trains 6 days a week

  • r/BodyHackGuideon Reddit

    Home - pin - shower - sleep. I sleep like never before and wake up fresh as a daisy. That’s been by far the biggest benefit for me

    • 1 point
    GlowingSleep5 months

    40-year-old on retatrutide plus CJC/ipa, strength training

  • r/Testosteroneon Reddit

    I did it for six months 5 days on 2 off and absolutly noticed a difference in muscle recovery and muscle mass. I was on a cut and able to gain muscle in a way that would have been hard to do with the limited calories.

    • 10 points
    PositiveRecovery & healing6 months, 5 on / 2 off

    CJC/ipa combo

  • r/Biohackingon Reddit

    I started cjc-1295 ipamorelin and was worried about the spike as diabetes was the main reason I started reta and peptides but I only saw a spike the first two doses

    • 7 points
    PositiveMetabolic & weight2+ months

    diabetic, also on retatrutide (which likely drove the HbA1c drop); fasts 4 h before the shot

  • r/BodyHackGuideon Reddit

    Zero sides for me, hot flushes for 5mins and great sleep👌I do take it with Ipamorelin tho.. seen some lean muscle gain and contractions/pump was noticeably better - think this was a placebo ordeal tho! Overall 6/10, don’t be expecting miracles!

    • 2 points
    PositiveSleep

    CJC-1295 with DAC plus ipamorelin; rates it 6/10

  • r/Peptidesourceon Reddit

    I haven't tried the no dac but the dac works great for me. I feel better for longer and i get good results so i'm happy with it. I notice decent muscle increase within a few weeks working out 2-3 times a week. I haven't noticed any adverse effects from it.

    • 2 points
    PositiveMetabolic & weight150 mcg DAC every morningInjection

    CJC-1295 with DAC plus GHRP-6

  • r/Biohackingon Reddit

    Def noticed less of a bulge in the belly and started seeing more muscle definition around weeks 9-12.

    • 2 points
    PositiveMetabolic & weight250 mcg CJC + 250 mcg ipamorelin nightly, 5 on / 2 offInjection12 weeks

    42-year-old on tirzepatide; tesamorelin added for the last 20 days

  • r/Biohackingon Reddit

    I also have good experience and currently on it. Body recomposing was sped up when I added it to Retatrutide.

    • 1 point
    PositiveMetabolic & weight1 mg DAC, injected after a mealInjection

    CJC-1295 with DAC on its own (dropped ipamorelin)

  • r/Biohackingon Reddit

    Sleep improvement is noticeable. I have an Apple Watch Ultra 2 and my sleep score has been in the mid 90's/100 most nights. Feel much more rested on waking. There has been some water retention.

    • 1 point
    PositiveSleeptwice dailyInjection8 weeks

    CJC no-DAC

  • r/BodyHackGuideon Reddit

    I do experience the flushing and pressure in my neck after injection and my sleep has been amazing but my cardio sessions have gotten progressively worse. My recovery is shit and I feel absolutely exhausted after a short time.

    • 3 points
    MixedRecovery & healing100-200 mcg CJC + 200-400 mcg ipamorelin, 5 on / 2 offInjection~3.5 weeks

    CJC no-DAC + ipamorelin

  • r/Retatrutideon Reddit

    I'm on week 2 of CJC+IPA (200 mcg + 200mcg) and the flushing effect is a little annoying.

    • 2 points
    MixedSleep200 mcg CJC + 200 mcg ipamorelin, eveningsInjection2 weeks

    mid-40s man on retatrutide

  • r/BodyHackGuideon Reddit

    I can already feel a noticeable difference in the firmness and size of chest / arm muscles.

    • 1 point
    MixedMetabolic & weight3 weeks

    prescribed CJC/ipa, keto and calorie restriction

  • r/BodyHackGuideon Reddit

    I’m on my 2nd week of cjc dac 800mcg and I’ve noticed deeper sleep but struggling to actually get up, I feel refreshed once I am up though.

    • 1 point
    MixedSleep800 mcg DACInjection2 weeks

    CJC-1295 with DAC

  • r/Peptidesourceon Reddit

    This represents roughly an 11% increase, which seems fairly underwhelming.

    • 6 points
    NothingMetabolic & weight100 mcg CJC no-DAC + 100 mcg ipamorelin nightlyInjection6 weeks

    written as a "subject"; UK vendor; baseline and follow-up labs

  • r/Biohackingon Reddit

    CJC + Ipamorelin isn't going to help you gain muscle. It's going, to help you recover a little better and some people will sleep better using it. It honestly didn't do much for me.

    • 5 points
    NothingMetabolic & weight

    CJC/ipa combo

  • r/Biohackingon Reddit

    I tried the DAC version for a while because the less frequent dosing fit my schedule better. Never saw any crazy results but the convenience was worth it

    • 4 points
    NothingMetabolic & weight

    CJC-1295 with DAC, chosen for less frequent dosing while travelling

  • r/BodyHackGuideon Reddit

    I’m on week 5 of this stack. I haven’t really noticed to much of a change. I might be a little bit leaner while staying in a caloric surplus, but sleep and recovery seem to be about the same.

    • 3 points
    NothingRecovery & healing5 weeks

    26-year-old in a surplus; CJC/ipa combo

  • r/Biohackingon Reddit

    I only did two doses until I noticed my resting heart rate inclining well past where I was comfortable.

    • 15 points
    Negative2 doses

    CJC no-DAC + ipamorelin

  • r/Biohackingon Reddit

    On day three on cjc-1295 no DAC. I do 2 units (100 mcg) every morning and night injected to my upper glute. I’ve been getting these itchy rashes all over vody but it is tolerable.

    • 7 points
    Negative100 mcg twice dailyInjection3 days

    CJC-1295 no-DAC on its own; first peptide ever

  • r/BodyHackGuideon Reddit

    Took two shots a week apart and I am completely exhausted. I should have started at a much lower dose and titrated up, that was my first mistake. I also regret going with the DAC.

    • 3 points
    NegativeMetabolic & weight2 mg DAC weeklyInjection2 shots a week apart

    46-year-old; CJC-1295 with DAC plus ipamorelin

  • r/BodyHackGuideon Reddit

    I’m On 150mcg cjc/ipa. Im on day 5 and It disturbs my sleep significantly. My hear rate is noticeably higher than normal at night.

    • 2 points
    NegativeSleep150 mcg CJC/ipaInjection5 days
  • r/Biohackingon Reddit

    It caused me to turn red and gave me migraine headaches when I was prescribed it. I did it for 8 weeks to "allow my body to adjust" then told my NP to never recommend that garbage again after my IGF-1 number didn't even budge.

    • 1 point
    NegativeMetabolic & weight8 weeks

    prescribed CJC/ipa by a nurse practitioner after six months of sermorelin; also had no IGF-1 response to MK-677

  • r/Biohackingon Reddit

    CJC/Ipa caused a nice little rosacea outbreak for me. That was nine months ago or so, and it’s still not quite resolved.

    • 1 point
    Negative

    CJC/ipa combo; no such problem on HGH

  • r/BiohackingUon Reddit

    Then suddenly I had a scary reaction after 2 days off. More than a flush: —my heart rate spiked from 66 to 126 extremely quickly. —my arms and hands turned bright red and were itchy. —I had pulsing tinnitus ringing in both ears.

    • 58 points
    Bad reactionMetabolic & weight200 mcg CJC + 200 mcg ipamorelin + 200 mcg GHRP-2, 4 nights/weekInjection~10 weeks

    doctor-supervised; escalating reaction came after 2 days off

  • r/Biohackingon Reddit

    From the very first pin I noticed the affects were much stronger than my first cycle. Rapid heart beat, dizziness, and swollen throat.

    • 13 points
    Bad reaction~300 mcg/dayInjection2 months, then restarted after a month off

    CJC/ipa from a US vendor; quit for good

  • r/BodyHackGuideon Reddit

    I had severe allergy from the CJC/IPA 10mg - strong hives all around abdomen/arms and sides, strong nausea as well with a strong sweating

    • 6 points
    Bad reaction200 mcg, then 100 mcg from a new vialInjection2 doses

    CJC/ipa 10 mg blend, on retatrutide

  • r/Biohackingon Reddit

    I had a bad reaction to CJC about 7 days into taking it. Without warning, and the very moment the the needle pierced my skin my HR ROCKETED to redline and my entire face/eyes went red - had to call an ambulance.

    • 4 points
    Bad reaction~7 days
  • r/BodyHackGuideon Reddit

    I literally passed out on CJC /IPA once, my blood pressure dropped way too much. The doctor said it was a Vasovagal response.

    • 2 points
    Bad reaction

    CJC/ipa combo; a doctor called it a vasovagal response

  • @James9thLifeon X

    CJC/Ipa started having issues, massive welts lasting for days (compounded product, not RUO)

    • 136 likes
    Bad reactionInjectionvendor-adjacent

    n=1 experience with compounded product

Research notes, not medical advice. Updated .

Sequence

The peptide's chain of amino acids from its start (the N-terminus) to its end, one bead and one letter for each: A alanine, C cysteine, D aspartic acid, E glutamic acid, F phenylalanine, G glycine, H histidine, I isoleucine, K lysine, L leucine, M methionine, N asparagine, P proline, Q glutamine, R arginine, S serine, T threonine, V valine, W tryptophan, Y tyrosine. A modification such as an N-acetyl cap or a C-terminal amide changes how long it lasts in the body. Length tells related peptides apart, from a two-residue dipeptide like carnosine to a 43-residue protein like thymosin beta-4, and predicts neither effect nor safety.

Report grades

Every first-hand Reddit or X report is graded on its own, from glowing through positive, mixed, nothing and negative to bad reaction, and the bar shows how those grades split. Posts that look vendor-adjacent stay on the peptide's page but are left out of the counts.

GlowingPositiveMixedNothingNegativeBad reaction

% positive

The share of a peptide's graded Reddit and X reports that are glowing or positive, vendor-adjacent posts left out. A peptide with few reports is pulled toward the average of all reports, as if it had eight average ones besides its own, so two glowing posts cannot top the list. Peptides rank by this figure, those with no graded report yet after those with one, and Avoid ones after every other entry.

Researcher estimate

No first-hand report of this peptide has been graded yet, so the figure is the researchers' own rating out of 10 from what they read about it. It ranks after every peptide with graded reports until its own arrive.

Safety tier

Each peptide is tiered Clean, Caution or Avoid from its five risk axes under the chosen safety bar. An Avoid peptide carries a real risk of harm, a plausible route to serious harm rather than mere unpleasantness, so it stays listed with the reason but ranks behind every other entry, however good its reviews.

Safety bar

The safety bar sets how much risk it takes to rate a peptide Avoid. Strict: out on any serious mechanism with little human data, or any documented serious harm. Balanced: out on documented serious harm (unless it is obvious, reversible and from a regulated product), or a serious mechanism whose harm would be silent with no human data at all. Evidence only: out only on documented serious harm in humans that is lasting, delayed or from grey-market product.

Seen harm

Documented serious adverse events in humans, from 0 for none despite real exposure to 3 for deaths or several well-documented serious harms. Serious means a hospital or emergency visit or harm lasting weeks, so a headache or a bad night does not count.

Mechanism

A plausible biological route to serious harm at the doses people use, such as growth-factor signalling, hormone-axis suppression, heart or blood-pressure effects or immune activation. It runs from 0 when none is known to 3 when a dangerous pathway has been shown in living animals.

Data gap

How little human safety data exists for the molecule actually sold, from 0 for an approved drug with large trials and years of use to 3 for no human safety data at all. A modified analogue does not inherit its parent's trials.

Silent harm

Whether the feared harm would show quickly or stay hidden, from 0 when it is obvious and goes on stopping to 3 when it is silent and delayed, like tumour promotion or slow organ damage. User reports cannot reveal a harm that takes years to appear, so a high score here limits what good reviews can tell you.

Product

The risk of what people actually buy, from 0 for a regulated pharmacy or supplement product taken by mouth or on the skin to 3 for a grey-market injectable. In one dataset of 6,441 grey-market samples, 42–71% failed basic quality criteria and 15% carried endotoxin; taken by mouth or in the nose, a pack avoids the injection risks.

Evidence

The strongest kind of study behind the peptide's effects, from an approved drug through human controlled trials and small human studies to animal work or nothing of its own. Animal results often fail to carry over to people.

Access

How people get it: as an approved drug, a compounded prescription, an over-the-counter supplement or from the grey market, where nobody checks the vial. The channel decides both the legal position and the risk of a bad batch.

Price per month

Thirty days of the typical dose, from its low end to its high end, priced at the listing a careful buyer would choose: in stock, from a shop scoring 4 of 5 on trust (third-party tested where no score is set), failing that 3, a pure pack before a blend, a European shop first, then the cheapest per mg. The range is the dose's, not the shops'. A per-dose amount counts once a day unless the dose says otherwise. The shop table keeps each listing's price per mg, per gram for bulk supplements. Where no listing can be priced the researchers' own estimate stands in, and says so.

Dose users report

The middle half of the daily doses stated in at least five first-hand reports, vendor posts left out. Where its middle sits more than twice above or below the declared dose, the month is priced at it as well, since what people take is what they pay for.

Shop trust

Each shop's trust on a 1–5 scale, read from its testing and its reputation: 1 for serious red flags (fabricated COAs, scam reports, impersonation, a closed shop), 2 for no public testing, a new shop or active complaints such as seized parcels, 3 for its own COAs or a short track record, 4 for verified third-party testing or a strong reputation, and 5 for third-party batch reports that name the shop, with years of good independent reputation. A shop without a score counts third-party batch testing as 4, its own COAs as 3 and no public tests as 2.

Best value

Within a category or a goal, a peptide that no other beats on both counts: none is rated more positively for the same or a lower monthly price, and none costs less for the same or a higher rating. The chart joins these into the best-value line; the cheapest of them and the best-rated of them both make it, so the line spans the trade-off from cheap to best. Avoid entries never count, and a peptide needs both a % positive and a price to be compared.

Testing

Whether the shop publishes lab results: third-party tested means an independent lab checks each batch, own COA means the shop's own certificate of analysis, and no public tests means neither. A certificate shows purity, not safety.

Added peptide

Some packs sold under one peptide's name hold a second one, such as 5 mg GHK-Cu in a nasal kit, stated only in the description. Sprayed in the nose or injected it reaches the blood like an injection, so it carries the risk of that route and is tiered as the injectable form, whatever its tier on the skin. A pack whose page gives no contents list may hold more than its name.