PepRank

N-Acetyl Selank Amidate

48%positive21 reports

Also: NA-Selank-Amidate · NA-Selank

CautionSocialFocusNasal / Injection

Stabilised, stronger Selank variant for anxiety; less data, more side reports.

TKPRPGP · N-acetyl, C-amide (7 residues)

TKPRPGP N-acetyl, C-amide

#12 of 61 research peptides · updated
Access
Grey market
Cost / month
≈ €27–72
researchers' estimate; no listing to price
Felt in 0 min – 1 h, lasts 6–8 h
21 user reports
Glowing 1Positive 9Mixed 4Nothing 5Negative 2
  • r/NooTopics· · 5 upvotesOriginal ↗

    I've used N-Acetyl-Selank from science(dot)bio in conjunction with naSemax and found to to dramatically reduce and pretty much eliminate social anxiety.

    GlowingSocial

    N-acetyl Selank from Science.bio, stacked with NA-Semax

  • r/NooTopics· · 6 upvotesOriginal ↗

    So far the N acetyl Selank amidate nasal spray I made helps with GAD but none of the supplements or anything else really works for me besides phenibut and alcohol

    PositiveNasal

    benzo taper; home-made N-acetyl Selank amidate spray

  • r/NooTopics· · 5 upvotesOriginal ↗

    I tried regular Selank, NA Selank, and Semax from everychem. Can't say I really felt anything at all tbh

    NothingNasal

    tried regular and NA-Selank sprays

Users report
Fewer reports than plain Selank. Fans describe stronger anxiolysis per spray; others note a morning-after hangover, lowered libido, or the same 'out of it' reactions as Selank. Roughly 35-45% feel little.
Best effects
Anxiolysis at lower dose than Selank · calm during social situations · stacks with GB-115 for anxiety
Downsides
Next-morning hangover/grogginess · lowered libido (isolated reports) · dizziness or emotional lability after a strong first dose
Evidence
No studies of its own — For the modified form (parent Selank is approved in Russia)
Caveat
No specific harm path, but no clinical data on the modified molecule and dosing is easy to overshoot.
Typical use
150-300 mcg/day nasal; start below plain-Selank doses.
Getting it
Research-chemical nasal sprays and lyophilized vials only; the modified molecule is not approved anywhere.
Stacked with
NA-Semax-Amidate: The usual pairing, often sold as a combined spray: NA-Semax for drive in the morning, NA-Selank to calm in the evening. · GB-115: Combined or used situationally for anxiety; users say NA-Selank calms thoughts while GB-115 relaxes the body. · PE-22-28: Occasional subq pairing for stress resilience; anecdotal only.

User reports 21

  • r/NooTopics· · 5 upvotesOriginal ↗

    I've used N-Acetyl-Selank from science(dot)bio in conjunction with naSemax and found to to dramatically reduce and pretty much eliminate social anxiety.

    GlowingSocial

    N-acetyl Selank from Science.bio, stacked with NA-Semax

  • r/NooTopics· · 6 upvotesOriginal ↗

    So far the N acetyl Selank amidate nasal spray I made helps with GAD but none of the supplements or anything else really works for me besides phenibut and alcohol

    PositiveNasal

    benzo taper; home-made N-acetyl Selank amidate spray

  • r/NooTopics· · 5 upvotesOriginal ↗

    I've tried semax /selank and also na semax /na selank. Feeling wise, they are identical. Just the na versions last longer. Like 8 hours or more for the na versions Vs the normal versions like 4-5 I think.

    Positive1 mg/day · Injection

    has used plain and NA forms

  • r/NooTopics· · 5 upvotesOriginal ↗

    I don’t understand how ppl rate it higher than NA selank, when selanks effects are immediate.

    Positive

    panic attacks; preferred it to GB-115

  • r/NooTopics· · 4 upvotesOriginal ↗

    The NA-Selank, first 2 bottles I tried, were “calm focus”. I liked that. You weren’t extra tired. You could still work but in a much more chill flow state. Absolutely awesome.

    PositiveFocus · Nasal

    Everychem NA-Selank spray, compared with plain Selank

  • r/NooTopics· · 3 upvotesOriginal ↗

    I also combine with the NA Selank spray which I also do one spray in each side 3 times a day. I LOVE the Selank. I think it works better than subq.

    Positive1 spray per nostril 3x/day · Nasal

    combined with GB-115 spray

  • r/NooTopics· · 2 upvotesOriginal ↗

    I’ve noticed that it has much more of a body relaxation effect in comparison to Selank which I feel calms my mind more than the body.

    PositiveSocial · Nasal

    uses NA-Selank and GB-115 situationally

  • r/BodyHackGuide· · 1 upvotesOriginal ↗

    I'd describe selank effects as a subtle calm clarity. I started IN and now subq NA SELANK. Subq + NA= same effect + longer duration. I'll take NA over regular any day.

    PositiveInjection

  • r/NTNPerformance· · 1 upvotesOriginal ↗

    I inject as needed after loading the first week do 1 mg and it works as advertised… the dose they purpose doesn’t do anything

    Positive1 mg as needed after a loading week · Injection

  • r/BodyHackGuide· · 1 upvotesOriginal ↗

    Yes, use it and love it. I use the NA amidate version, injectable. Also take with pe-22-28 and can handle any stress that comes my way.

    PositiveInjection

    NA amidate, stacked with PE-22-28

  • r/Biohacking· · 2 upvotesOriginal ↗

    There’s a noticeable hangover effect the morning after Selank, and an urge to find relief the next morning with the Semax.

    Mixed400 mcg at night · Nasal · 5-7 days

    alongside NA-Semax amidate subq

  • r/NooTopics· · 1 upvotesOriginal ↗

    NA-Selank works but i need a big dose 1000mcg its subtle but at least it doesn't feel like a placebo.

    Mixed1000 mcg · Nasal

  • r/NooTopics· · 1 upvotesOriginal ↗

    Just pinned my first dose of N-Acetyl Selank amidate 250mcg/10units (Subq) And feeling like I've had a drink in a good way, 2nd dose this afternoon 6:30pm (250mcg/10units), Same effect but this time it's screwed with my taste buds

    Mixed250 mcg twice a day · Injection · first day

  • r/Biohacking· · 1 upvotesOriginal ↗

    I have noticed in the past week, since the advent of my NA selank amidate cycle, that it has significantly lowered.

    Mixed300 mcg · 1 week

  • r/NooTopics· · 5 upvotesOriginal ↗

    I tried regular Selank, NA Selank, and Semax from everychem. Can't say I really felt anything at all tbh

    NothingNasal

    tried regular and NA-Selank sprays

  • r/Biohackers· · 2 upvotesOriginal ↗

    I’m having the same dilemma been spraying up to 3 mg NA Selank per day and it’s not all that

    Nothingup to 3 mg/day · Nasal

  • r/BodyHackGuide· · 2 upvotesOriginal ↗

    I have been using for about a week and haven’t noticed anything. I started with 200mcg in the AM and increased to 600mcg in the AM. Haven’t noticed anything other than feeling a little tired.

    Nothing200-600 mcg each morning · Nasal · 1 week

    Selank amidate spray shipped without ice in heat

  • r/NooTopics· · 1 upvotesOriginal ↗

    And honestly, I was rather disappointed. I didn't expected anything like Vyvanse or something but I actually felt little to nothing.

    Nothing2 sprays in the evening · Nasal

    ADHD, on Vyvanse; Everychem sprays with NA-Semax

  • r/Biohackers· · 1 upvotesOriginal ↗

    I got some from BioLabs but it wasn’t effective.

    Nothing

    NA-Selank/NA-Semax from a UK vendor

  • r/Biohackers· · 1 upvotesOriginal ↗

    Ya I was dizzy and emotional for about 4-5 days then it went away completely. Pretty sure it didn’t mix well when reconstituting and I got a mega dose.

    Negative100 mcg/spray, likely an uneven home-mixed dose · Nasal · single dose

  • r/FinasterideSyndrome· Original ↗

    Took Selank a peptide for anxiety and mixed with Buspar. Has anyone tried this combo, today I feel like a zombie, max brain fog.

    Negative

    combined with buspirone; post-finasteride syndrome

Safety

Tier by safety barStrict CautionBalanced CautionEvidence only Clean

Seen harmMechanismData gapSilent harmProduct

Seen harm 0/3
About twenty first-hand reports describe grogginess, fog and, after one likely mega-dose, a few days of dizziness and emotional lability; none serious. The zero reflects community use only. r/Biohackers: dizzy and emotional for 4-5 days after a likely mega-dose of NA-Selank ↗
Mechanism 1/3
Selank's sequence with capped ends, so the same speculative GABA-A and enkephalinase effects; no harm pathway is known. Volkova et al. 2016: Selank shifts GABAergic gene expression in rat cortex (PubMed 26924987) ↗
Data gap 3/3
No human or toxicology data exist for the modified molecule; plain Selank's small Russian trials bridge only partly, because capping is meant to change potency and duration. Zozulia et al. 2008: Selank vs medazepam in GAD and neurasthenia, n=62 (PubMed 18454096) ↗
Silent harm 1/3
Reported effects are felt within hours and resolve within days of stopping.
Product 2/3
Research-chemical nasal sprays and lyophilised vials only, some injected. Mendias & Awan 2026 preprint: 6,441 grey-market peptide samples, 42-71% failed quality criteria, 15% had endotoxin ↗
Never if
Pregnancy or breastfeeding (no human reproductive data)

Where to buy 4 in Europe · 15 total

ShopFormPricePer mgTesting
Nootropic SourceUSpowder · 30 mg€4954.95 USD€1.65/mgOwn COA
Baltic PeptidesEU · LTpowder · 30 mg€60€2.00/mgThird-party tested
Baltic PeptidesEU · LTspray · 30 mgcontents not stated€65€2.17/mgThird-party tested
Limitless Biotech (Limitless Life Nootropics)USsolution · 30 mg€6775.09 USD€2.25/mgNo public tests
Limitless Biotech (Limitless Life Nootropics)USspray · 30 mg€7078.09 USD€2.34/mgNo public tests
Limitless Biotech (Limitless Life Nootropics)USsolution · 20 mg€4853.09 USD€2.38/mgNo public tests
Limitless Biotech (Limitless Life Nootropics)USspray · 20 mg€5056.09 USD€2.52/mgNo public tests
Limitless Biotech (Limitless Life Nootropics)USpowder · 30 mg€7886.99 USD€2.61/mgNo public tests
Limitless Biotech (Limitless Life Nootropics)USpowder · 20 mg€5358.99 USD€2.65/mgNo public tests
Limitless Biotech (Limitless Life Nootropics)USspray · 30 mg€8189.99 USD€2.70/mgNo public tests
Limitless Biotech (Limitless Life Nootropics)USspray · 20 mg€5661.99 USD€2.78/mgNo public tests
Nootropic SourceUSspray · 20 mg€5865 USD€2.92/mgOwn COA
Nootropic SourceUSspray · 10 mg€3135 USD€3.14/mgOwn COA
Baltic PeptidesEU · LTspray · 10 mgcontents not stated€40€4.00/mgThird-party tested
Modern Peptides EUEU · DEpowder · 10 mg€45€4.50/mgOwn COA

Studies 3

Sources 2

More in Mood & anxiety all 5 →

  1. 1GB-115 GW (2 residues) Caution Nasal / Sublingual / Oral≈ €22–54 / month57%positive41 reportsDipeptide-like CCK-receptor blocker; daytime anxiolytic without sedation or blunting.
  2. 2Oxytocin (intranasal) CYIQNPCLG (9 residues) Caution Nasal≈ €27–90 / month52%positive50 reportsBrief social warmth and lower social anxiety; subtle, short-lived for most.
  3. 3Selank TKPRPGP (7 residues) Caution Nasal / Injection≈ €5.7–11 / month50%positive48 reportsNon-sedating anxiolytic; quiets rumination and social anxiety without benzo-style dependence.
  4. 4PE-22-28 GVSWGLR (7 residues) Excluded Nasal / Injection≈ €36–140 / month54%positive29 reportsTREK-1-blocking spadin fragment; fast-acting antidepressant in mice.No human data, and it blocks a channel whose loss makes animals more prone to seizures and ischaemic injury.

Sequence beads

Each bead is one amino acid in the peptide's chain, coloured by its side chain: grey for non-polar, cyan for polar, blue for positively charged and fuchsia for negatively charged. Length and mix tell related peptides apart at a glance, from a two-residue dipeptide like carnosine to a 43-residue protein like thymosin beta-4. The colours describe chemistry only and predict neither effect nor safety.

non-polarpolarpositivenegative

Report grades

Every first-hand Reddit or X report is graded on its own, from glowing through positive, mixed, nothing and negative to bad reaction, and the bar shows how those grades split. Posts that look vendor-adjacent stay on the peptide's page but are left out of the counts.

GlowingPositiveMixedNothingNegativeBad reaction

% positive

The share of a peptide's graded Reddit and X reports that are glowing or positive, vendor-adjacent posts left out. A peptide with few reports is pulled toward the average of all reports, as if it had eight average ones besides its own, so two glowing posts cannot top the list. Kept peptides rank by the same reports' mean grade, shrunk the same way, and excluded ones follow in that order.

Researcher estimate

No first-hand report of this peptide has been graded yet, so the figure is the researchers' own rating out of 10 from what they read about it. It ranks alongside the computed scores until reports arrive.

Safety tier

Each peptide is tiered clean, caution or excluded from its five risk axes under the chosen safety bar. An excluded peptide has a plausible route to serious harm, so it stays listed with the reason but ranks behind every other entry, however good its reviews.

Safety bar

The safety bar sets how much risk it takes to exclude a peptide. Strict: out on any serious mechanism with little human data, or any documented serious harm. Balanced: out on documented serious harm (unless it is obvious, reversible and from a regulated product), or a serious mechanism whose harm would be silent with no human data at all. Evidence only: out only on documented serious harm in humans that is lasting, delayed or from grey-market product.

Seen harm

Documented serious adverse events in humans, from 0 for none despite real exposure to 3 for deaths or several well-documented serious harms. Serious means a hospital or emergency visit or harm lasting weeks, so a headache or a bad night does not count.

Mechanism

A plausible biological route to serious harm at the doses people use, such as growth-factor signalling, hormone-axis suppression, heart or blood-pressure effects or immune activation. It runs from 0 when none is known to 3 when a dangerous pathway has been shown in living animals.

Data gap

How little human safety data exists for the molecule actually sold, from 0 for an approved drug with large trials and years of use to 3 for no human safety data at all. A modified analogue does not inherit its parent's trials.

Silent harm

Whether the feared harm would show quickly or stay hidden, from 0 when it is obvious and goes on stopping to 3 when it is silent and delayed, like tumour promotion or slow organ damage. User reports cannot reveal a harm that takes years to appear, so a high score here limits what good reviews can tell you.

Product

The risk of what people actually buy, from 0 for a regulated pharmacy or supplement product taken by mouth or on the skin to 3 for a grey-market injectable. In one dataset of 6,441 grey-market samples, 42–71% failed basic quality criteria and 15% carried endotoxin.

Evidence

The strongest kind of study behind the peptide's effects, from an approved drug through human controlled trials and small human studies to animal work or nothing of its own. Animal results often fail to carry over to people.

Access

How people get it: as an approved drug, a compounded prescription, an over-the-counter supplement or from the grey market, where nobody checks the vial. The channel decides both the legal position and the risk of a bad batch.

Price per month

Thirty days of the typical dose, from its low end to its high end, priced at the listing a careful buyer would choose: in stock, from a shop scoring 4 of 5 on trust (third-party tested where no score is set), failing that 3, a pure pack before a blend, a European shop first, then the cheapest per mg. The range is the dose's, not the shops'. A per-dose amount counts once a day unless the dose says otherwise. Prices are in euros at ECB rates of 2026-10-29, before shipping; the shop table keeps each listing's price per mg, per gram for bulk supplements. Where no listing can be priced the researchers' own estimate stands in, and says so.

Dose users report

The middle half of the daily doses stated in at least five first-hand reports, vendor posts left out. Where its middle sits more than twice above or below the declared dose, the month is priced at it as well, since what people take is what they pay for.

Testing

Whether the shop publishes lab results: third-party tested means an independent lab checks each batch, own COA means the shop's own certificate of analysis, and no public tests means neither. A certificate shows purity, not safety.

Added peptide

Some packs sold under one peptide's name hold a second one, such as 5 mg GHK-Cu in a nasal kit, stated only in the description. Sprayed in the nose or injected it reaches the blood like an injection, so it carries the risk of that route and is tiered as the injectable form, whatever its tier on the skin. A pack whose page gives no contents list may hold more than its name.