Antibiotics were working, introduce the LL-37 and within 3 weeks the infection cleared. I used it on half dose to avoid a bad flu that was going round but it cleared up my athletes foot like no other cream before, 3 months in and I'm still all clear
GlowingInjection
own athlete's foot, plus a relative's cellulitis foot infection already on antibiotics; half dose
Killed all the nad crap. Was a rough ride for 5 weeks. Tongue got pink again, no more bloating and all the other crap that comes with h pylori , sibo and candida
GlowingGut · Injection · 5 weeks
H. pylori, SIBO, candida and mould exposure; stacked with BPC-157
I have tried all 3, oral and injected BPC157 and noticed no difference from any of them on gut symptoms.
NothingGut
SIBO gut symptoms; also tried KPV and BPC-157
Strict case
Pro-inflammatory/autoimmune and context-dependent pro-tumour activity, plus FDA-noted reproductive effects.
Users report
There are few reports. Some credit it with clearing long-running low-grade infections or cellulitis alongside antibiotics, or with dysbiosis. Others feel 'off' with worst-ever brain fog or Herxheimer-type reactions, and many keep it only for acute illness because of the risks discussed.
Pro-tumorigenic in ovarian, breast and lung cancer models (FDA note) · Drives autoimmune inflammation (psoriasis, lupus) and is found in atherosclerotic plaque · FDA: nonclinical detrimental effects on male reproduction
Evidence
Small human studies — Topical phase 2 for venous leg ulcers; injectable use animal only
Typical use
100-250 mcg/day subQ in short courses.
Getting it
Research-peptide vendors only; on the FDA's Category 2 list, so US pharmacies cannot compound it, and users report it getting harder to find. No approved product anywhere.
Stacked with
Thymosin alpha-1: The usual partner in Lyme and mould protocols, taken to support immunity while LL-37 is the antimicrobial; also what users credit for some of the die-off. · BPC-157 and KPV: Gut stacks for SIBO, H. pylori and candida; users who improved on these stacks cannot separate the peptides. · Binders (charcoal, zeolite, cholestyramine): Taken to blunt die-off reactions, alongside a lower starting dose.
Antibiotics were working, introduce the LL-37 and within 3 weeks the infection cleared. I used it on half dose to avoid a bad flu that was going round but it cleared up my athletes foot like no other cream before, 3 months in and I'm still all clear
GlowingInjection
own athlete's foot, plus a relative's cellulitis foot infection already on antibiotics; half dose
Killed all the nad crap. Was a rough ride for 5 weeks. Tongue got pink again, no more bloating and all the other crap that comes with h pylori , sibo and candida
GlowingGut · Injection · 5 weeks
H. pylori, SIBO, candida and mould exposure; stacked with BPC-157
Helped me to cure chronic sinusitis, I was so tired of using antibiotics every month! Used in spray, 200 mcg daily, reconstituted with colloid silver water
Glowing200 mcg/day · Nasal
chronic sinusitis; spray made up with colloidal silver water
I actually think it helped me fight off a low grade infection that I’ve had for years. I don’t have any bad reactions and I read the study that was just shared. Short term use and low doses seems the safest.
LL37 is great for colonized mold, Lyme cysts and I believe bad bacteria and viruses too. It has definitely gone after the fungus in my lungs. Day 1 of injecting it and I had die off.
PositiveInjection · second round (first one 2 years earlier)
colonised Aspergillus; stacked with thymosin alpha-1, TB-4, KPV/BPC-157 and daily HBOT
It's hard to separate the SS-31 and the LL-37 as I resumed taking SS-31 very shortly before beginning LL-37, but I think I have more energy than last time I was taking SS-31. I think it's likely the LL-37 is helping.
Dont feel compelled to use a certain dose as there is no such thing. The doses are all just made up. So use what you can tolerate. I used 1mg and it worked great.
Positive1 mg
advice to someone who reacted badly: lower the dose
Increased herx responses and better looking live blood tests. Was doing in combination with daily herbs, bi-weekly IVs (nano copper/silver, NAC, Resveratrol, etc), and Thymosin Alpha 1 peptide (5 days a week).
Positive~125 mcg/day, 30 days on / 30 off · 3 cycles over a year
chronic Lyme; heavily confounded with herbs, IVs and thymosin alpha-1
First day got bad die off which made me feel fluish and gave me vertigo. Then after that agitation after my night shot for a couple of days. But on the positive I usually get really depressed during the full moon. Not this month.
I started it about 4 weeks ago after the first two doses Istarted having some herxing. I lowered my dose and it has improved. I am also taking a couple other peptides my symptoms are improving.
Mixed4 weeks
Lyme; started after 30 days of doxycycline, with other peptides and Buhner herbs
I’m 2 weeks in 250mcg daily of it under a protocol with a doctor. I’ve felt a general “off” feeling, I’d say my brain fog is also at its absolute worst.
Negative250 mcg/day · 2 weeks
doctor-run protocol for high mycotoxin and heavy-metal labs
After being sick for 2 weeks I decided to tap into the LL-37 in hopes I could force the virus out. The next 3 days felt like I should've been on hospice lol.
I dosed it twice at very low doses and after the second dose I woke up the next morning with my face so swollen I could barely see. It took a week to go away and damaged the moisture barrier on my face.
Bad reactionvery low (2 then 6 units of a 3 ml vial) · 2 doses
Within 5 hours of that injection, I got slammed with body aches to the level of "herx", and LL-37 has a known side effect of causing this by too big of a cytokine response.
NegativeInjection · 2 doses · vendor-adjacent
taken at the first sign of an infection
Safety
Tier by safety barStrict ExcludedBalanced CautionEvidence only Caution
Psoriasis, lupus or other autoimmune disease · Active cancer or a history of cancer · Trying to conceive (male reproductive effects in animals) · Pregnancy or breastfeeding (no human reproductive data)
Each bead is one amino acid in the peptide's chain, coloured by its side chain: grey for non-polar, cyan for polar, blue for positively charged and fuchsia for negatively charged. Length and mix tell related peptides apart at a glance, from a two-residue dipeptide like carnosine to a 43-residue protein like thymosin beta-4. The colours describe chemistry only and predict neither effect nor safety.
non-polarpolarpositivenegative
Report grades
Every first-hand Reddit or X report is graded on its own, from glowing through positive, mixed, nothing and negative to bad reaction, and the bar shows how those grades split. Posts that look vendor-adjacent stay on the peptide's page but are left out of the counts.
GlowingPositiveMixedNothingNegativeBad reaction
% positive
The share of a peptide's graded Reddit and X reports that are glowing or positive, vendor-adjacent posts left out. A peptide with few reports is pulled toward the average of all reports, as if it had eight average ones besides its own, so two glowing posts cannot top the list. Kept peptides rank by the same reports' mean grade, shrunk the same way, and excluded ones follow in that order.
Researcher estimate
No first-hand report of this peptide has been graded yet, so the figure is the researchers' own rating out of 10 from what they read about it. It ranks alongside the computed scores until reports arrive.
Safety tier
Each peptide is tiered clean, caution or excluded from its five risk axes under the chosen safety bar. An excluded peptide has a plausible route to serious harm, so it stays listed with the reason but ranks behind every other entry, however good its reviews.
Safety bar
The safety bar sets how much risk it takes to exclude a peptide. Strict: out on any serious mechanism with little human data, or any documented serious harm. Balanced: out on documented serious harm (unless it is obvious, reversible and from a regulated product), or a serious mechanism whose harm would be silent with no human data at all. Evidence only: out only on documented serious harm in humans that is lasting, delayed or from grey-market product.
Seen harm
Documented serious adverse events in humans, from 0 for none despite real exposure to 3 for deaths or several well-documented serious harms. Serious means a hospital or emergency visit or harm lasting weeks, so a headache or a bad night does not count.
Mechanism
A plausible biological route to serious harm at the doses people use, such as growth-factor signalling, hormone-axis suppression, heart or blood-pressure effects or immune activation. It runs from 0 when none is known to 3 when a dangerous pathway has been shown in living animals.
Data gap
How little human safety data exists for the molecule actually sold, from 0 for an approved drug with large trials and years of use to 3 for no human safety data at all. A modified analogue does not inherit its parent's trials.
Silent harm
Whether the feared harm would show quickly or stay hidden, from 0 when it is obvious and goes on stopping to 3 when it is silent and delayed, like tumour promotion or slow organ damage. User reports cannot reveal a harm that takes years to appear, so a high score here limits what good reviews can tell you.
Product
The risk of what people actually buy, from 0 for a regulated pharmacy or supplement product taken by mouth or on the skin to 3 for a grey-market injectable. In one dataset of 6,441 grey-market samples, 42–71% failed basic quality criteria and 15% carried endotoxin.
Evidence
The strongest kind of study behind the peptide's effects, from an approved drug through human controlled trials and small human studies to animal work or nothing of its own. Animal results often fail to carry over to people.
Access
How people get it: as an approved drug, a compounded prescription, an over-the-counter supplement or from the grey market, where nobody checks the vial. The channel decides both the legal position and the risk of a bad batch.
Price per month
Thirty days of the typical dose, from its low end to its high end, priced at the listing a careful buyer would choose: in stock, from a shop scoring 4 of 5 on trust (third-party tested where no score is set), failing that 3, a pure pack before a blend, a European shop first, then the cheapest per mg. The range is the dose's, not the shops'. A per-dose amount counts once a day unless the dose says otherwise. Prices are in euros at ECB rates of 2026-10-29, before shipping; the shop table keeps each listing's price per mg, per gram for bulk supplements. Where no listing can be priced the researchers' own estimate stands in, and says so.
Dose users report
The middle half of the daily doses stated in at least five first-hand reports, vendor posts left out. Where its middle sits more than twice above or below the declared dose, the month is priced at it as well, since what people take is what they pay for.
Testing
Whether the shop publishes lab results: third-party tested means an independent lab checks each batch, own COA means the shop's own certificate of analysis, and no public tests means neither. A certificate shows purity, not safety.
Added peptide
Some packs sold under one peptide's name hold a second one, such as 5 mg GHK-Cu in a nasal kit, stated only in the description. Sprayed in the nose or injected it reaches the blood like an injection, so it carries the risk of that route and is tiered as the injectable form, whatever its tier on the skin. A pack whose page gives no contents list may hold more than its name.