I was so doubtful at first, I didn’t even see decent results until 2ish months in. When you are genuinely starch white it takes significantly longer which I feel like isn’t talked about much here.
My skin was darker than I’d ever seen it. Patches on my lips had changed colors. New moles were emerging like someone was drawing on me with a permanent marker. ... I wasn’t injecting BPC-157. I was injecting melanotan II
Bad reactionInjection · about a week
vial sold as BPC-157 for a knee turned out to be melanotan II
It works for tanning, even in skin type 1, and users love the results. Under 10% see nothing. Nausea, stomach cramps, flushing, spontaneous erections and darkening/new moles are near-universal talking points. ER doctors report priapism.
Best effects
Deep tan with less UV · less burning · libido increase
Small human studies — Early 2000s trials; otherwise case reports
Typical use
Community: 250-500 mcg loading, then maintenance every 1-2 weeks. Users report 71–300 mcg/day (median 130 mcg, n=9).
Getting it
Never approved anywhere, and regulators (FDA, UK MHRA, Australian TGA) warn against it. Sold as research-peptide vials and nasal sprays online and through tanning salons and gyms.
Stacked with
Melanotan I: The common plan is to build a base with MT2, then maintain with MT1 for a more natural colour, fewer moles and less nausea. · Antihistamine (cetirizine) or ondansetron before the dose: Several users say it largely removes the nausea and flushing; others find nothing helps. · Sun or sunbed right after dosing: The community insists on UV straight after injecting to avoid patchy freckles and moles; the published melanoma case involved sunbeds. · Tadalafil or sildenafil: Taken for the libido effect; the combination and overdoses are where priapism reports come from. · GLP-1 agonists (retatrutide, tirzepatide): Often run together on Reddit; some find the combined nausea much worse, and one first-dose vomiting and muscle-spasm report came a week after starting retatrutide.
I was so doubtful at first, I didn’t even see decent results until 2ish months in. When you are genuinely starch white it takes significantly longer which I feel like isn’t talked about much here.
I dosed 0.25 daily for the first few days and then worked up to 0.5- I have been doing a 9 min sunbed every other day and just doing the school run in uv 4/5 also. No nasty side effects and only felt flushed on my first dose.
Glowing0.25 mg/day rising to 0.5 mg, then twice a week · Injection · almost 3 weeks
skin type 1 ginger, 9-minute sunbed every other day
Holy fucking shit this stuff works quick. Just got back from Mexico and I got the most tan I’ve ever been since high school. I only took two small dosages of 100mcg and got crazy results
Glowing100 mcg twice, with 10-minute tanning bed sessions · Injection
It was interesting, my first couple weeks I didn’t feel like I was making much progress, then BANG. One time I came out of the sunbed and I caught myself in the mirror
Glowing150 mcg rising to 400 mcg, 30 minutes before a sunbed every 3 days · 3 months
This peptide honestly has such a fascinating social effect for me. It is subtle but definitely noticeable. It’s hard to describe in words, but I feel more socially lucky on this peptide.
PositiveSocial · 40-75 mcg a few times a week · Injection · 6 months
I hate the Melanotan-2 (MT-2) nausea that can come with it, so I stopped trying. But being at the beach for a week, I grabbed my nuts and decided to use it. Within 2 hours of one dose, I already look like I should be detained by ICE.
Dark spots/moles. Yes, they will show up and it puts a lot of people off (it put me off at first but I persevered) It's my opinion that these moles have always been there
I personally had brief darkening of freckles but that evened out as the tan set in. Once the tan was there it was extremely even and natural looking. The MT2 nausea gets me badly at >150mcg.
I was surprised at how well it worked. I am someone with very light skin. Was born with blonde, almost white hair and blue eyes. I shouldn't be able to get beyond a very mild tan. I was able to get a decent tan that I'd never had before.
for me my hair ALWAYS gets darker. I go from being Irish-reddish blondish brown to dark brown. I love MT-2 it’s the only way I can transition from an Irish pale skin to a Dominican in less than a week.
Positive250 mcg/day for a week, then 250 mcg weekly
I've been on it 14 years apart from a year break in lockdown. It was odd going back to being white at the end of a year after being dark tanned for for so long lol. Soon came back though.
The first cycle I used it too heavy in the beginning and I got darkened freckles. They went away after I stopped. Every year thereafter I noticed no negative side effects.
I took MT2 for 13 days, then went to Europe (peak summer heat wave). That was 3 months ago. I'm still tan and I haven't burned. Moles definitely got darker though - only downside.
I’ve been using it for ten years this month on and off from the same company. I had so many concerns when I started and sometimes still get nervous but I’ve had no adverse effects aside from your typical flushing etc.
I use MT2. The tan for me is a little more orangeish. I use it to get a decent base tan to prevent sunburns, sun damage and have some color. Great before sex too.
It varies person to person but for me I feel like garbage for an hour or two after pinning it. And that’s the main reason why I haven’t used it in a long time. ... But it’s very very effective if you’re willing to make that trade off
Mixedabout 2x/week, only on tanning days · Injection
Used Melanotan-2, three doses the week before a 5-day trip to Cabo. Didn’t need any sunscreen for the first 3 days. ... Definitely got tanner but I didn’t feel like it was noticeable enough to post pics.
MT2, severe nausea at a very low dose (500mcg) which lasts about 8 hours. But, the tan is darker and quicker. Easy to overdo it and people can tell you are on it because it's less natural color.
I used MT2 for over a decade around 2 two week cycles per year and got great results with tanning. Noticed when I use it now I am getting some minor freckling on the face so stopped using it.
Melanotan 2 was always a favorite of mine for how fast it tans you, but that comes at a cost. After getting a bunch of moles, Including a very sketchy one, I decided it wasn't for me
I still have lots more tiny moles than I ever had originally, and every so often new ones appear. They are a constant reminder of my stupidity in ever taking MT2 and I hope I don’t get skin cancer or anything in years to come as a result.
I noticed that about the moles too. They darken way faster than the skin on MT2. Probably the biggest reason I switched to MT1. That and the nausea I got on 2.
the side effects. ughhh they are horrible for some people, and I was one of those people who got it bad even on a very low dose. Vomiting, nausea, chills, etc and that really put me off from using it again.
My skin was darker than I’d ever seen it. Patches on my lips had changed colors. New moles were emerging like someone was drawing on me with a permanent marker. ... I wasn’t injecting BPC-157. I was injecting melanotan II
Bad reactionInjection · about a week
vial sold as BPC-157 for a knee turned out to be melanotan II
Yesterday I pulled my GHK-Cu, HGH, then HCG into a syringe and then pulled 400mcg of MT2 accidentally. Didn’t want to waste so I pinned it. I’m absolutely miserable. Feverish and nauseous.
Bad reaction400 mcg by accident · Injection
accidental dose drawn into a syringe with other peptides
I had a tiny mole cut off a few weeks ago (after 3+ months of consistent MT2 use) and it came back as "atypical intraepidermal melanocytic proliferation" or AIMP for short.
Bad reaction3+ months
pathology called it not cancerous but highly abnormal; causality unknown
When I took my first dose of MT2 the other night I got extremely hot, puked violently and had involuntarily muscle spasms and twitches, I felt like I was going to have a seizure.
Bad reaction250 mcg (first dose) · Injection
116 lb woman, also started retatrutide and GHK-Cu the week before; later tolerated 50-100 mcg
I developed Choroidal neovascularization (CNV) using it. So be careful. Cnv is the growth of abnormal blood vessels from the choroid through Bruch's membrane into the retina. Basically blind in center of one eye.
I regret trying this, - no change in color/pigmentation. However, after I take it within a few hours my legs feel sorta "noodle" like or lack of full leg control, last about 24 hours.
I will say it until I’m blue in the face: Melanotan 2 is the best peptide on earth. Nothing makes you look and feel better than a tan. Additionally, you get better erections, increased libido, and appetite suppression.
I ran it for the tan, and it delivered, until I looked deeper into what I was putting in my body. ... the nausea, the blood pressure spikes, and the heavy facial flushing.
been sleeping well and don’t feel hungover the next day like MT2 did to me. ... I’d say if you can tolerate mt2 well then probably more bang for the buck there but mt1 jives with me better since I seemed to be more sensitive.
Mixedvendor-adjacent
compares with Melanotan I; account sells peptides
Safety
Tier by safety barStrict ExcludedBalanced ExcludedEvidence only Excluded
Personal or family history of melanoma, or many or atypical moles · Hypertension or cardiovascular disease · History of priapism · Pregnancy or breastfeeding (no human reproductive data)
Each bead is one amino acid in the peptide's chain, coloured by its side chain: grey for non-polar, cyan for polar, blue for positively charged and fuchsia for negatively charged. Length and mix tell related peptides apart at a glance, from a two-residue dipeptide like carnosine to a 43-residue protein like thymosin beta-4. The colours describe chemistry only and predict neither effect nor safety.
non-polarpolarpositivenegative
Report grades
Every first-hand Reddit or X report is graded on its own, from glowing through positive, mixed, nothing and negative to bad reaction, and the bar shows how those grades split. Posts that look vendor-adjacent stay on the peptide's page but are left out of the counts.
GlowingPositiveMixedNothingNegativeBad reaction
% positive
The share of a peptide's graded Reddit and X reports that are glowing or positive, vendor-adjacent posts left out. A peptide with few reports is pulled toward the average of all reports, as if it had eight average ones besides its own, so two glowing posts cannot top the list. Kept peptides rank by the same reports' mean grade, shrunk the same way, and excluded ones follow in that order.
Researcher estimate
No first-hand report of this peptide has been graded yet, so the figure is the researchers' own rating out of 10 from what they read about it. It ranks alongside the computed scores until reports arrive.
Safety tier
Each peptide is tiered clean, caution or excluded from its five risk axes under the chosen safety bar. An excluded peptide has a plausible route to serious harm, so it stays listed with the reason but ranks behind every other entry, however good its reviews.
Safety bar
The safety bar sets how much risk it takes to exclude a peptide. Strict: out on any serious mechanism with little human data, or any documented serious harm. Balanced: out on documented serious harm (unless it is obvious, reversible and from a regulated product), or a serious mechanism whose harm would be silent with no human data at all. Evidence only: out only on documented serious harm in humans that is lasting, delayed or from grey-market product.
Seen harm
Documented serious adverse events in humans, from 0 for none despite real exposure to 3 for deaths or several well-documented serious harms. Serious means a hospital or emergency visit or harm lasting weeks, so a headache or a bad night does not count.
Mechanism
A plausible biological route to serious harm at the doses people use, such as growth-factor signalling, hormone-axis suppression, heart or blood-pressure effects or immune activation. It runs from 0 when none is known to 3 when a dangerous pathway has been shown in living animals.
Data gap
How little human safety data exists for the molecule actually sold, from 0 for an approved drug with large trials and years of use to 3 for no human safety data at all. A modified analogue does not inherit its parent's trials.
Silent harm
Whether the feared harm would show quickly or stay hidden, from 0 when it is obvious and goes on stopping to 3 when it is silent and delayed, like tumour promotion or slow organ damage. User reports cannot reveal a harm that takes years to appear, so a high score here limits what good reviews can tell you.
Product
The risk of what people actually buy, from 0 for a regulated pharmacy or supplement product taken by mouth or on the skin to 3 for a grey-market injectable. In one dataset of 6,441 grey-market samples, 42–71% failed basic quality criteria and 15% carried endotoxin.
Evidence
The strongest kind of study behind the peptide's effects, from an approved drug through human controlled trials and small human studies to animal work or nothing of its own. Animal results often fail to carry over to people.
Access
How people get it: as an approved drug, a compounded prescription, an over-the-counter supplement or from the grey market, where nobody checks the vial. The channel decides both the legal position and the risk of a bad batch.
Price per month
Thirty days of the typical dose, from its low end to its high end, priced at the listing a careful buyer would choose: in stock, from a shop scoring 4 of 5 on trust (third-party tested where no score is set), failing that 3, a pure pack before a blend, a European shop first, then the cheapest per mg. The range is the dose's, not the shops'. A per-dose amount counts once a day unless the dose says otherwise. Prices are in euros at ECB rates of 2026-10-29, before shipping; the shop table keeps each listing's price per mg, per gram for bulk supplements. Where no listing can be priced the researchers' own estimate stands in, and says so.
Dose users report
The middle half of the daily doses stated in at least five first-hand reports, vendor posts left out. Where its middle sits more than twice above or below the declared dose, the month is priced at it as well, since what people take is what they pay for.
Testing
Whether the shop publishes lab results: third-party tested means an independent lab checks each batch, own COA means the shop's own certificate of analysis, and no public tests means neither. A certificate shows purity, not safety.
Added peptide
Some packs sold under one peptide's name hold a second one, such as 5 mg GHK-Cu in a nasal kit, stated only in the description. Sprayed in the nose or injected it reaches the blood like an injection, so it carries the risk of that route and is tiered as the injectable form, whatever its tier on the skin. A pack whose page gives no contents list may hold more than its name.